Nerve pain, especially in the legs, feet, and hands, is common among adults in the United States. Also called peripheral neuropathy, it affects up to 30% of adults, and nearly 10% of those over age 65. There are many causes of peripheral neuropathy, including: diabetes vitamin deficiencies trauma Infection immune diseases medications or chemicals Chronic nerve pain interferes with daily activities. Symptoms of burning or shooting pain, numbness and tingling